JIPMER PG SOLVED PAPER DOWNLOAD FOR YOUR EXAM PREPARATION PDF

JIPMER PG SOLVED PAPER DOWNLOAD FOR YOUR EXAM PREPARATION PDF Describe the etiology and pathogenesis ofchildhoodasthma.Describeassessmentofasthmaseverityandkeyelements of optimum out-patient management of childhoodasthma.
Definition:
Asthmaisaheterogeneousdisease,usuallycharacterizedby
chronic airwayinflammation.Itis defined bythe historyof
respiratorysymptomssuchaswheeze,shortnessofbreath,chest
tightnessandcoughthatvaryovertimeandinintensity,together
withvariableexpiratoryairflowlimitation.
Etiology:
a)In the susceptible host,immune responses to common
airwaysexposures(e.g.,respiratoryviruses,allergens,tobacco
smoke,airpollutants)can stimulate prolonged,pathogenic
inflammationandaberrantrepairofinjuredairwaystissues.
b)Lung dysfunction (airwayshyperresponsiveness, reduced
airflow)andairwayremodelingdevelop.
c)These pathogenic processes in the growinglung during
earlylifeadverselyaffectairwaysgrowth and differentiation,

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