Andrews’ Diseases of the Skin: Clinical Dermatology 12th Edition
Andrews’ Diseases of the Skin: Clinical Dermatology diagnose and treat a wide range of skin conditions with the latest edition of the highly regarded Andrews’ Diseases of the Skin: Clinical Dermatology. The 12th edition of this classic reference, by esteemed authors William D. James, MD, Timothy G. Berger, MD, and Dirk M. Elston, MD, provides state-of-the-art information on newly recognized diseases, new conditions, and unusual variants of well-known diseases, as well as new uses for tried-and-true medications and unique drugs for diseases as disparate as melanoma and rosacea. It’s your ideal go-to resource for clinical dermatology, at every stage of your career.
Andrews’ Diseases of the Skin: Clinical Dermatology
The skin is the site of many complex and dynamic processes These process include Barrier and immunologic functions, melanin production, vitamin D synthesis, sensation, temperature regulation, protection from trauma and aesthetics.
The epidermal barrier protects the skin from microbes, chemicals, physical trauma, and desiccation due to transepidermal water loss.
This barrier is created by differentiation of keratinocytes as they move from the basal cell layer to the stratum corneum. The keratinocytes of the epidermis are produced and renewed by stem cells in the basal layer resulting in replacement of the epidermis every 28 days.
I takes 14 days for these cells to reach the stratum corneum and another 14 days for the cells to desquamate.