Congenital Syphilis in 5min – Must Know Essential Points
Early manifestation of congenital infection vary and involve multiple organ systems.
- About 60% of infants born with congenital syphilis are asymptomatic at birth
- Symptoms develop within the first 2 months of life . In symptomatic infants , the most common physical finding, seen in 100% of cases , is hepatomegaly.
- The other common findings are skeletal abnormalities, rash ,and generalised lymphadenopathy.
- Radiographic abnormalities, periostitis or osteitis , involve multiple bones . Sometimes, the lesion is painful and an infant will favour an extremely (pseudopalsy )
- The rash is maculopapular and may involve palms and soles . In contrast to acquired syphillis , a vesicular rash and Bullae may develop. These lesions are also highly contagious.
- Mucosal involvement may present as rhinitis ( snuffles ). Nasal secretions are highly contagious.
- Haematological abnormalities include anemia and thrombocytopenia.
Late onset congenital syphillis:
It is a common pattern of presentation for congenital syphillis and consists of three phenomena also called as Hutchinson triad
Manifestation also include :
- Bone involvement: saber shins , saddle nose.
- Teeth involvement : notched, peg shaped incisors ( Hutchinson teeth)
- Pigmentory involvement : linear scars ( rhagades) at the corner of the mouth
- Interstitial keratitis : present in the first or second decade of life .
- Sensory neural hearing loss ( CN VIII deafness)