Must know Points in Calcium Deficiency and Disorders for FMGE / NEET-PG

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    Must know Points in Calcium Deficiency and Disorders

     Must know Points in Calcium Deficiency and Disorders for FMGE / NEET-PG

    As we all know there a Some important Disease etiologies is due to Calcium Deficiency.Now we will see some important information or we can say must know concepts for Calcium Disorders.

    OSTEOMALACIA:

      In osteomalacia the serum calcium level is low , the phosphates are low , and alkaline phosphates are low , and alkaline phosphates is high.

    Pathophysiology :

      Lack of sunlight exposure, nutritional deficiency of Vitamin D , malabsorption syndrome, partial gastrectomy.

     Failure of absorption of calcium and phosphorus ( decreased serum calcium and phosphorus)

     Decreased turnover of calcium and phosphorus in bone matrix.

     Demineralisation of bone and bony substance replaced by soft osteoid tissue .

     Bone pains , muscular weakness (myopathy), spontaneous fractures.

     

    Disease Cause Radiological features
    Osteopetrosis Osteoclasts dysfunction Bone within bone appearance

    Rugger jersey spine

    Osteoporosis Loss of bone mass Cod fish vertebrae

    Penicilling – in -vertebrae

    Osteogenesis imperfecta Deficiency of synthesis of type1 collagen Thickened or deformed bone due to multiple fractures
    Osteomalacia Vitamin D deficiency Looser’s zone or pseudo fracture.
    Scurvey Vitamin C deficiency. Frenkel’s line , ring sign , thin cortex , Scurvey line
    Rickets Vitamin D deficiency Widening of growth plate , cupping of the metaphysis.